Signs and symptoms of peripheral neuropathy might include:
- Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms.
- Sharp, jabbing, throbbing or burning pain.
- Extreme sensitivity to touch.
Acute symmetrical peripheral neuropathy Rare, this severe, rapidly developing form of polyneuropathy affects nerves throughout the body and is most often seen in Guillain-Barré syndrome, an autoimmune disorder that attacks the peripheral nervous system and can be fatal.
People with advanced neuropathy may have problems sleeping, experience paralysis, muscle failure or problems with organs or other bodily functions. In many cases, neuropathy may begin with extremities, such as toes and fingers, and work itself up to the core of the body through the hands and feet.
Symptoms can range from mild to disabling and are rarely life-threatening. The symptoms depend on the type of nerve fibers affected and the type and severity of damage. Symptoms may develop over days, weeks, or years.
If the underlying cause of peripheral neuropathy isn't treated, you may be at risk of developing potentially serious complications, such as a foot ulcer that becomes infected. This can lead to gangrene (tissue death) if untreated, and in severe cases may mean the affected foot has to be amputated.
Peripheral neuropathy can cause pain and make it difficult to walk or do things with your hands.
Stage 5: Complete Loss of Feeling
You do not feel any pain, just intense numbness. This is because there are no nerves that are able to send signals to your brain. At this stage, walking has become very difficult, and your balance is severely affected. You may become so unsteady that you have to use a wheelchair.
There are several key factors that affect a patient's prognosis in familial amyloid polyneuropathy (FAP), but most people with the rare, inherited, progressive disease have a life expectancy of about 10 years after being diagnosed.
There are different stages of neuropathy, and each stage isn't always easy to recognize. But you must know each stage and understand it to the best of your ability. Treatment for peripheral neuropathy will help you deal with the pain, so it's important that you start treatment as soon as possible.
This type of nerve damage is usually only on one side of the body and can affect the hip, buttock, or thigh. Proximal neuropathy can cause severe pain and difficulty with movement, as well as weight and muscle loss.
Treatment for Peripheral Neuropathy in Adults
Our neurologists prescribe medication to treat neuropathy. A procedure called plasma exchange can help some people with peripheral neuropathy achieve remission.
It's usually caused by chronic, progressive nerve disease, and it can also occur as the result of injury or infection. If you have chronic neuropathic pain, it can flare up at any time without an obvious pain-inducing event or factor. Acute neuropathic pain, while uncommon, can occur as well.
Peripheral neuropathy means these nerves don't work properly. Peripheral neuropathy may occur because of damage to a single nerve or a group of nerves. It may also affect nerves in the whole body.
Neuropathy can affect nerves that control muscle movement (motor nerves) and those that detect sensations such as coldness or pain (sensory nerves). In some cases, it can affect internal organs, such as the heart, blood vessels, bladder, or intestines.
When those deposits build up, peripheral nerves start to malfunction, and the patient experiences peripheral neuropathy. The disease eventually involves sensory, motor and autonomic nerves, and it is fatal.”
Autonomic neuropathy can damage the nerves of the cardiovascular system, affecting heart rate and blood pressure: Blood pressure may drop sharply after you sit or stand, causing a feeling of lightheadedness. Heart rate may remain high or too low instead of fluctuating with body functions and exercise.
Neuropathic Pain and Treatment Options
Neuropathic pain is often described as a tingling or burning sensation, and peripheral neuropathy often causes pain and numbness in the hands and feet. Symptoms may improve if the neuropathy has an underlying condition that can be cured or better managed.
Regular exercise, such as walking three times a week, can reduce neuropathy pain, improve muscle strength and help control blood sugar levels. Gentle routines such as yoga and tai chi might also help. Quit smoking.
If you suffer from neuropathy, you have likely noticed that the pain, tingling, and other odd sensations are often much worse at night. This can make it very difficult to sleep at night, especially if the pain continues to increase.
Since burning sensations in the feet are a common symptom of people with neuropathy, you should know about the topical treatments that can help. Prescription treatments like SSRIs, Cymbalta, and Wellbutrin can help you if you have peripheral neuropathy symptoms.
With sensory peripheral neuropathy, nerve damage in the feet causes numbness, often as a result of diabetes or chemotherapy, leading to difficulties walking and a higher risk for falls.
Peripheral neuropathy is damage to the nerves outside the brain and spinal cord. Many people with peripheral neuropathy have feelings of severe tiredness (fatigue) that are not necessarily related to physical problems such as muscle weakness.
Walking with a wobbly motion or even losing your balance can result from diabetic peripheral neuropathy. Wearing orthopedic shoes often helps with this. Loss of coordination is a common sign of diabetic peripheral neuropathy.