Synvisc-One® (hylan G-F 20) is an injection that supplements the fluid in your knee to help lubricate and cushion the joint, and can provide up to six months of osteoarthritis knee pain relief.
Corticosteroid injections are among the most common knee injections. Doctors inject corticosteroids directly into the knee joint to help relieve knee pain and inflammation quickly.
Among the brands of hyaluronic acid are approved for knee OA:
- Synvisc, Synvisc-One.
Unfortunately, the results of gel shots are hard to predict. Some people have great outcomes, with pain relief that lasts for months. In other people, though, we don't see much improvement at all. Still, hyaluronic acid injections are approved for treating the knee joint, and are often covered by insurance.
How long the effects last varies. Some patients report pain relieving effects for several months following the injections. If the injections are effective they may be repeated after a period of time, usually 6 months.
You can have hyaluronic acid injections every six months or so. Many patients find that the injections provide enough relief that they can delay or even avoid knee replacement surgery.
Numerous studies have shown that the gel injections are no more helpful than cortisone injections. However, they do not harm the articular surface like cortisone. Unlike cortisone, 10%-20% of the patient may develop an adverse reaction to the shots and experience severe pain and swelling within 72 hours of injection.
In the United States, the estimated national average cost for one knee gel injection is $1,012.00. If your health care provider recommends that you get gel injections to relieve your knee pain and mobility issues, you should do your homework and make a decision based on what's best for your circumstances.
Sometimes, gel injections could worsen the pain. This increase in pain may be short-term only. However, in some cases, the knee becomes swollen and inflamed. In these cases, you might have experienced an allergic reaction.
The only difference is that Synvisc-One is provided with one injection, compared to the three injections required for SYNVISC. Both treatments can provide up to six months of osteoarthritis knee pain relief.
DUROLANE has been proven to provide greater reduction in knee pain versus Synvisc-One1* and longer lasting pain relief versus a steroid injection2. DUROLANE is also safe for repeated courses of therapy.
A nurse or trained healthcare professional will check you carefully and talk about whether the injection is suitable for you. They will give you the injection. You may receive between one and five injections, usually a week apart, depending on which brand of hyaluronic acid your healthcare professional uses.
Common Side Effects
The package insert for the arthritis injections says the most commonly reported problems associated with them include pain, swelling, heat, redness and fluid build-up around the knee. The manufacturer says these reactions are usually mild and don't last long.
Euflexxa contains a substance extracted from bacteria cells. Synvisc One uses a substance that comes from chicken combs. Both Euflexxa and Synvisc are effective at treating the pain and decreased mobility that accompany knee osteoarthritis.
Cortisone and hyaluronic injections are commonly used for fast, temporary relief from knee osteoarthritis pain. Cortisone injections may begin working within 24 hours of the injection, and the effects of a cortisone injection typically last between 6 weeks to 6 months.
To prevent pain and swelling, your doctor may recommend resting your knee or applying ice for a short time after your injection.
The cost for Synvisc-One intra-articular solution (48 mg/6 mL) is around $1,062 for a supply of 6 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Do not strain your knee joint for two days after receiving this medicine. Avoid activities such as jogging, soccer, tennis, heavy lifting, or standing on your feet for a long time. Temporary pain or swelling in the knee joint may occur after receiving hyaluronic acid injection.
How do I treat bone on bone knee pain? Treatments for bone on bone knee pain range from conservative treatments, such as exercise and bracing, to painkillers, and knee replacement surgery. Typically, multiple treatments are combined to treat bone on bone knee pain.
Yes, Medicare will cover knee injections that approved by the FDA. This includes hyaluronan injections. Medicare does require that the doctor took x-rays to show osteoarthritis in the knee. The coverage is good for one injection every 6 months.
Long-lasting results are one of the main reasons patients choose rooster comb injections over cortisone. Treatment generally involves a weekly injection three to five weeks in a row, and results can last up to six months.
There are few studies comparing Synvisc to corticosteroids, which makes it hard to draw a comparison. However, one study involving 100 patients compared Synvisc to betamethasone for knee osteoarthritis; the researchers found no difference at six months in pain or function between the two treatment groups.
Over-the-counter medications — such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve) — may help ease knee pain. Some people find relief by rubbing the affected knee with creams containing a numbing agent, such as lidocaine, or capsaicin, the substance that makes chili peppers hot.
Hyaluronic acid injection for the knee is usually considered a safe procedure, but like any medical procedure, it may carry some side effects and risks. The most common side effects of this procedure include mild swelling and pain at the injection site.